Genetics and postsurgical neuropathic pain
نویسندگان
چکیده
منابع مشابه
Genetics of neuropathic pain
Neuropathic pain affects numerous patients who have sustained damage to the nervous system. It remains unknown why only the minority of patients who sustain damage to the nervous system develops signs and symptoms of neuropathic pain, nor why treatments remain inadequate for many patients. This review highlights the evidence from animal studies of the genetic mechanisms of individual difference...
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Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and sensorial alterations at surgery area.Between years 2012 and 2015, 16 to 65 age...
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PURPOSE OF REVIEW Gabapentin and pregabalin bind to the alpha-2-delta calcium channel subunit and represent a novel analgesic drug class. The evidence base supporting their use for chronic neuropathic and early postsurgical pain is reviewed. RECENT FINDINGS Multiple, large, high-quality trials have demonstrated the safety and efficacy of gabapentin and pregabalin in neuropathic pain. Treatmen...
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Neuropathic pain results from damage to, or dysfunction of, the system that normally signals pain. The International Association for the Study of Pain (IASP 2007) defines neuropathic pain as follows: ‘Pain initiated or caused by a primary lesion or dysfunction in the nervous system. Peripheral neuropathic pain occurs when the lesion or dysfunction affects the peripheral nervous system. Central ...
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Capsaicin 8% patch (Qutenza) is mainly used to treat postherpetic neuralgia and human immunodeficiency virus-associated neuropathy. However, evidence of the efficacy of Qutenza in other forms of neuropathic pain is lacking. A 24-year old Libyan man, with no previous medical history, sustained multiple wounds in the right side of the chest and back after a bomb explosion. The patient experienced...
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ژورنال
عنوان ژورنال: European Journal of Anaesthesiology
سال: 2019
ISSN: 0265-0215
DOI: 10.1097/eja.0000000000000986